Evaluation of Antibody Response and Adverse Effects following Heterologous COVID-19 Vaccine Booster with mRNA Vaccine among Healthcare Workers in Indonesia
نویسندگان
چکیده
Background: The administration of the third (or booster) dose COVID-19 vaccine is important in maintaining protection against SARS-CoV-2 infection or severity disease. In Indonesia, health care workers (HCWs) are among first to receive a booster vaccine. this study, we evaluated antibody response and adverse events following heterologous using mRNA-1273 HCWs that were fully vaccinated with inactivated viral as priming doses. Methods: 75 at Dr. Soetomo General Hospital Surabaya, participated study. level receptor binding domain was analyzed 1, 3, 5 months second after dose. Results: We found significantly higher subjects receiving compared those an booster. Interestingly, participants hypertension history diabetes mellitus showed lower There frequency injection vaccine, although overall considered minor. Conclusions: A mRNA resulted high response; however, displayed response.
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ژورنال
عنوان ژورنال: Vaccines
سال: 2023
ISSN: ['2076-393X']
DOI: https://doi.org/10.3390/vaccines11071160